Memory Fitness Alzheimer's Treatment

Neuroscience has reversed the disease process! In Clinical Trials - the elan AN-1792 provides evidence of beta amyloid plaque clearance - First patholical alteration of disease process.  Brain Imaging Technologies Document Early Onset & Treatment Response Clilnical Memory Fitness Tests Detect Early Onset Years Earlier Now - Making the administration of FDA Approved Treatments More Effective Hundreds of Drug & Research Teams Are Progressing Towards Having More Effective Treatments The Population Has Prevention Treatments, FDA approved treatments, and Many Treatments In Clinical Trials

Alzheimer's Treatment Progress

For 100 years, doctors, researchers and care givers have sought a cure - or even an effective treatment -
that would slow, arrest or reverse the Alzheimer's disease process. Until the end of the 20th Century,
there were no FDA approved Alzheimer's treatments. Doctors like J.Wesson Ashford were instrumental
in introducing treatments at the clinical level, while another group of researchers were pushing innovative
treatment concepts into their laboratories.

Until the 1980's most Alzheimer's research was conducted by individual doctors or researchers, who
worked in isolation and often without funds or equipment. As more and more was learned about the
disease process and its relationship with a healthy body, a number of pharmaceutical treatments
were developed.

There are a handful of organizations that raise funds for research, as well as conduct seminars,
manage research projects, and distribute educational and/or informational programs regarding ending
Alzheimer's. I have established relationships with these groups and would like you to visit with them as well.
The organizations and the individuals maintaining them, in some cases compete with one another - but
always unite in the common cause of ending this terrible disease.

Alzheimer's Research Forum - This group regularly conducts seminars, debates, and
publishes discussions as well as progress reports. This group collects the research
and opinions from the leading neuroscience doctors, researchers, technologists and
treatment development specialists - a must visit if you are interested in the latest
Alzheimer's research findings.

Registered Researchers of the Alzheimer's Research Forum

Alzheimer's Education and Referral Center - This multi-facetted online collection of reports,
publications, videos, is operated by National Institute on Aging and holds vast archived
information as well as free booklets, regular updates on FDA approved treatments and
often information about NIA funded research projects.

International Brain Research Organization - This is not only a good source of historic
and generic information about Alzheimer's (brain) research - if represents a collection
of schools, research projects, researchers and institutions working in Alzheimer's
related fields.

Dr. J. Wesson Ashford's works within the laboratory and the clinic environments. He has seen
the development of FDA approved drugs come into practice while he was developing his memory
testing and mild cognitive impairment screening programs.

Medical Doctors have traditionally (for the past 100 years) been the front line of Alzheimer's
detection and treatment strategy development. Unfortunately, the doctors have had little of no
access to effective Alzheimer's screening tests - and less awareness of treatments - even the
FDA approved treatments.

The FDA process (clinical trials) that bring treatments from the laboratory to the doctors), are conducted under strict confidence - to protect the patients and the research/treatment
development group's liability. As recently as 1999, I conducted online searches for doctors,
treatments, clinics and cures for Alzheimer's - and I found several posted articles, testimonies,
and clinical "treatment" centers offering more than hope to the online reader.

I tried to investigate or visit each of these promoters and only found a few that were sincere.
In some cases, the promoters were little more than health and fitness zealots - promoting the
truth that the right diet matched to the right physical/mental regimes - promotes health. Others
were out and out misinformed promoters. I wasn't the only one checking around for an effective Alzheimer's treatment platform.

At the 2000 Stockholm Alzheimer's conference, the research and medical communities
agreed to agree that the Alzheimer's disease process was accurately diagnosed by Dr. Alzheimer
in 1906, and that all of the research that followed his diagnosis led to the overwhelming conclusion
that Alzheimer's was a degenerative process - meaning caused by environmental and individual
lifestyle elements; and that changing an at risk individual's lifestyle habits towards those that
reduced that individual's chances of developing the disease (PREVENTION), was the best
treatment yet developed.

Short of press releases and an occasional story leaked by the leading doctor's or their PR firms,
little information trickled to the to Medical Doctors who examine individuals at risk of developing Alzheimer's.

I asked Dr. Ashford to comment on the FDA approved Alzheimer's disease treatments, and how
he felt they could help end Alzheimer's.

How can it be? How can so many people be robbed of their memory, dignity, worth and
independence, and not have adequate advocacy to merit serious funding and a concentrated
research effort?

There is probably a million answers to that question. From my point of view, it seemed to be
a matter of awareness and money. Awareness in a global sense that Alzheimer's costs
Americans $125 Billion a year - and it could be prevented if self administered treatments
are promoted between the doctors and the populations.

The pharmaceutical industry uses a set of rules/guidelines and business practice disciplines - basically a handbook - when developing drugs with high financial values.

Part of these guidelines - the part that moves a drug from the clinical trials into clinics - presently constitutes a massive marketing effort on the half of the drug companies. I'm not making any
judgment here -I'm simply the messenger. And, I'm reporting that companies spending/investing
$200-700,000 on the developing of a new drug/treatment - have to generate their return on investment
by any means available.

The FDA strictly monitors and prescribes (which is kind of ironic - the FDA prescribing practice
policies to the doctors)

The Alzheimer's Vaccine and Immunetherapy

The first reversal of the Alzheimer's disease process - has been documented from the first human clinical trials of the Alzheimer's Vaccine compound. Over 300 Alzheimer's patients were inoculated with the Alzheimer's vaccine in clinical trials. A small percentage of them developed inflammation in the memory centers of their brains. The dosages were halted for safety reasons - but the research continues.

Now there has been published autopsy reports, from very credible doctors - providing evidence that the beta amyloid plaques were cleared from the disease brain's memory centers.

Continued research of the living patients provide evidence that the memory fitness - the patient's ability to form recent memories - either stabilized (didn't get worse) or got better!

Doctors and researchers have the first foundation to investigate further - and they are. The Neurological Disease Foundation hosted " The Great Debate" during the 2004 Neuroscience Convention in San Diego California. This one hour debate contains the Con arguments of Dr. Todd Golde, MD, PhD of the Mayo Clinic, and, the Pro sides presented by Dr. Peter Davies, PhD of Albert Einstein College of Medicine Department of Pathology and Neurosciences.

The convention was attended by thousands of researchers and doctors - and over three hundred of them attended the debate. I was there and produced a complete video of the activity - I urge you to show it to your doctors - and, if you are interested in hearing the best researchers in this area outline their current approach to ending Alzheimer's - you will find this fascinating.

There are still mysteries of this complex disease, but so much is know now and associated technologies like memory testing and brain imaging - researchers now have effective ways of measuring monitoring diseased as well as healthy human brains. Dr. Alzheimer and most of the researchers that followed him, had to wait for diagnosis confirmation at autopsy. We've come a long, long way.

The development of Immunetherapy has caused a revolution within the Neuroscience community. I'll try to summarize why.

• Until recently, researchers only speculated about the role a beta amyloid played in healthy as well as diseased brains. Today, not only is the role beta amyloid plays in healthy brains understood (normal levels), the relationship between the normal levels, excessive levels and blood chemistry provide additional evidence of disease onset.
• When Dr. Schenk developed the Alzheimer's Vaccine theory (first in mice then moving into human trials) - there was a common assumption that the blood/brain barrier - the isolation of the brain from the circulatory system's anti-body and immunity systems) - prevented the basic immune functions within the cranial cavity (skull). The first participant (was administered the vaccine in clinical trials) to die (not from clinical trial related issues), at autopsy provided evidence the middle stage plaque deposits were cleared from the disease brain. A growing number of research projects have now duplicated Dr. Schenk's mice models - and are advancing their research towards human trials.
• After initial inoculations, a small percentage of the over 300 patients developed inflammation - so dosage was halted - but the research continued. It was found that patients who received the vaccine, had their memory performance stabilize or get better.
• The Alzheimer's LifePlan, Dr. Ashford, and The Neurological Disease Foundation, have joined forces and launched the Memory Assessment Project - which validate the clinical versions of Dr. Ashford's short term memory and learning performance testing platform within Alzheimer's treatment clinical trials.
• Clearly, the mechanism of stimulating the body's anti-body/immune responses that clear the beta amyloid plaque from the short term memory forming areas of the brain - have a positive effect for the patients - and could lead to an effective treatment - not a cure - but a treatment that allows people to live normal lives with their Alzheimer's condition being managed.

Of course, the promise of promises would be that early inoculation with a safe vaccine to those at high risk of developing the Alzheimer's disease process - could prevent development of the disease in their remaining lifetime.

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